The right food for dogs with liver diseases or impaired liver function.

Features

• Copper reduction: reduces liver damage.
• Hydrolyzed soy protein
• Chelated zinc
• Adequate level of metabolizable energy

Indication

• Chronic inflammatory lesions
• Chronic liver failure
• Hepatic encephalopathy
• Portosystemic shunt
• Ascites

Administration Period

This product should be administered for the entire life if there is chronic liver disease, or for a certain period of time depending upon the regenerating capacity of the liver. A periodic evaluation needs to be done to analyze the condition and frequency of feeding.

Feeding Guideline

Weight, kg

Daily Amount

Weight, kg

Daily Amount

1

23 g

25

261 g

2.5

46 g

30

299 g

3

53 g

35

336 g

7

100 g

40

371 g

10

131 g

45

406 g

15

178 g

50

439 g

20

221 g

60

503 g

Contraindication

Puppies, pregnant, and lactating female dogs.

Nutritional Analysis

Crude Protein (min.) 15%, Fat (min.) 18%, Fibers (max.) 3.5%, Moisture (max.) 10%, Mineral Matter (max.) 5.5%, Calcium (max.) 0.7%, Phosphorus (min.) 0.4%, Copper (max.) 0.0005%, Probiotic (min.) 1%. Metabolizable energy: 4,070 kcal / kg.

Basic Composition

Medium grain rice, Chicken giblets, Hydrolyzed soy protein, Corn gluten gluten 60, Ground whole corn, Flaxseed, Chicken fat (tocopherol and rosemary essence), Refined fish oil, Powdered egg, Beetroot pulp, Brewer’s dry yeast, Probiotic, Mannan-oligosaccharides, Inulin, Zeolite, Sodium chloride (common salt), Potassium chloride, Yucca schidigera extract, Calcium propionate, L-carnitine, DL-methionine, Taurine, Tryptophan, Dicalcium phosphate, Chicken liver hydrolyzate, Vitamin supplement, Trans-chelated micromineral supplement.

Enrichment

Vitamin A 20000 IU, Vitamin B12 100 mcg, Vitamin C 100 mg, Vitamin D 1000 IU, Vitamin E 500 IU, Selenium 0.5 mg, Folic Acid 1.8 mg, Pantothenic Acid 20 mg, Iron 100 mg, Iodine 2 mg, Copper 5 mg, DL-methionine 8000 mg, L-carnitine 2000 mg, Tryptophan 2000 mg , Sodium 1.5 g, Potassium 7 g, Magnesium 900 mg, Manganese 18 mg, Vitamin B1 10 mg, Vitamin B2 14 mg, Vitamin B6 10 mg, Vitamin H 0.8 mg, Vitamin K 1.5 mg, Vitamin PP 100 mg, Zinc 200 mg, Taurine 2000 mg.

Clinical Considerations

Among the main challenges of veterinary medicine the physiological and metabolic disturbances involving the liver stand out. Liver disease is often complicated by inappetence that promotes metabolic tissue loss. Dietary control of the disease requires a fairly palatable diet, despite protein restriction, and very digestible, in order to reduce the catabolic state. These general recommendations supplement dietary nutrient modifications, for example, proteins, lipids, and carbohydrates.

In chronic liver disease, an alteration in protein metabolism occurs and a reduction in albumin synthesis, which corresponds to 60% of the total plasma protein, which can lead to ascites and edema.

The liver plays an important role in the degradation of proteins from the diet and in the deamination of some amino acids. Some aromatic amino acids, such as tyrosine, phenylalanine, and tryptophan, are generally removed from the portal circulation and metabolized by the liver; With liver disease, those amino acids accumulate in the circulation. Veterinary Hepatic Balance – HE has 14% protein and its source is of vegetable origin, which helps protein metabolism without exceeding the capacity of the liver.

Dietary therapy should provide sufficient protein to support liver regeneration, repair, and maintenance, minimizing nitrogenou s products resulting from protein catabolism.

Blood glucose can be maintained with 1⁄4 of the liver’s functional capacity, but declining glucose circulation (hypoglycemia) can occur in cases of cirrhosis, liver failure, or liver malignancy. The Diet Balance Veterinary Hepatic – HE has in its formulation a highly digestible carbohydrate, rice, which is also very appetizing.

The liver is very important in lipid metabolism, where fatty acids are synthesized and stored as triglycerides. When liver glycogen is reduced, fatty acids are mobilized from adipose tissue, and then oxidized by the liver. Carnitine is a necessary cofactor for the transport of fatty acids from the cytoplasm to the mitochondria, and the liver is important in the metabolism of carnitine. Veterinary Hepatic Balance – HE is composed of L-Carnitine and the ideal content of Ethereal Extract to increase energy density and thus ensure adequate intake of nutrients in smaller portions and sufficient amounts of food.

Vitamin and mineral deficiency may occur related to liver disease, as a consequence of the association of poor food intake, reduced intestinal absorption and increased needs resulting from catabolism and liver regeneration. That is why Equilibrio Veterinary Hepatic – HE contains a vitamin complex with a high content of fat-soluble vitamins A, D, E, K and B Complex that helps in storage and absorption.

Minerals like iron, copper, and zinc are stored in the liver. The accumulation of copper can cause further liver damage and can occur both due to defects in copper metabolism and as a result of decreased copper excretion. In liver disease, the accumulation of Cu in hepatocytes is likely due to inadequate excretion in bile, with consequent poisoning and worsening liver disease. Zinc can reduce the intestinal absorption of copper by competition between ions and influence the synthesis of metallothionein, a copper-binding protein that binds to intestinal copper by excreting it in bile and reducing its absorption. Zinc deficiency can produce and the magnesium concentration can also be decreased in cases of cirrhosis. Balance Veterinary Hepatic HE contains low copper content and adequate concentrations of chelated zinc, reducing the risks of copper poisoning.

The ideal level of metabolizable energy, which provides adequate caloric intake, is an important aspect to be considered in animals with liver disorders.

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